Osteosarcoma

[Mary]

ADULT ONSET OSTEOSARCOMA
Osteogenic Sarcoma in Patients Older Than Forty, 2006


BIOPSY
Osteogenic Sarcoma of the Patella Spread to Lateral Meniscus after Arthroscopy - This case report shows the importance of a thorough evaluation of the patient’s complaints, careful review of imaging studies, including MRI, before a diagnostic biopsy is done. The biopsy must avoid the possibility of tumor contamination of the joint.


TREATMENT
Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival
Improvement in Histologic Response But Not Survival in Osteosarcoma Patients Treated With Intensified Chemotherapy


RISK OF ADDITIONAL CANCERS
Second Malignant Neoplasm in Patients With Osteosarcoma of the Extremities Treated With Adjuvant and Neoadjuvant Chemotherapy, 2006


METASTASIS and RECURRENCE
Second and Subsequent Recurrences of Osteosarcoma, 2009
Excision of pulmonary metastases of osteogenic sarcoma of the limbs.
Multimodal treatment of osteosarcoma lung metastases.
Predictors of long-term survival with pulmonary metastasectomy for osteosarcomas and soft tissue sarcomas, 2006
Pulmonary resection for metastatic osteosarcomas: a retrospective analysis of 21 patients, 2006
Low-dose methotrexate inhibits lung metastasis and lengthens survival in rat osteosarcoma, 2006
Bone metastases in osteosarcoma patients treated with neoadjuvant or adjuvant chemotherapy: the Rizzoli experience in 52 patients.


Parosteal Osteosarcoma
Oncologic outcome of parosteal osteosarcoma, 2006
Dedifferentiation of Parosteal Osteosarcoma, 2001

Periostal Osteosarcoma
Periosteal osteosarcoma: long-term outcome and risk of late recurrence, 2006
Periosteal Osteosarcoma: Long-term Outcome and Risk of Late Recurrence


SURVIVAL
Survival Statistics, 2007 - Please consider whether or not you WANT to know these statistics before reading!


FIBULA
Fibular Osteosarcomas: Contaminated Margins May Not Impact Survival, 2006


HUMERUS
Osteosarcoma of the Proximal Humerus: Long-Term Results With Limb-Sparing Surgery, 2002


The Fluoride Debate - Relevant Medical Studies
Caution needed in fluoride and osteosarcoma study, 2006
Age-specific fluoride exposure in drinking water and osteosarcoma (United States), 2006
Systematic review of water fluoridation, 2000

[Mary]

Impact of family structure on long-term survivors of osteosarcoma

Main results:  Ten patients showed mild functional impairments; only five patients were handicapped more seriously. Depressive symptoms were diagnosed in four patients. A total of six patients revealed unbalanced family structures, including three of the four patients with depressive symptoms, all four patients with symptoms of posttraumatic stress disorder, and five of seven patients who showed poor emotional acceptance.

Conclusions:  Osteosarcoma survivors will generally recover good functional performance. Only a minority of them remain seriously impaired. One third of the patients present depressive symptoms and posttraumatic stress disorder. Poor coping is closely associated with unbalanced family structures. Therefore, the psychological and familial situation of patients with newly diagnosed osteosarcoma should be carefully assessed.

Mary's thoughts - It might be a good idea to seek family or individual counseling if you find you are having significant difficulties adjusting to life after osteosarcoma. If there is lack of support or positive interaction in your family unit, there are things to do for yourself or your family that might help.